Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Benadryl and plaquenil Hydroxychloroquine sulphate in sweden Lower back or side pain noisy breathing painful or difficult urination red irritated eyes red skin lesions, often with a purple center severe mood or mental changes sore throat sores, ulcers, or white spots on the lips or in the mouth sticking out of the tongue stomach pain swelling of the feet or lower legs swollen or painful glands What are some other side effects of Plaquenil? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Not hungry. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Bad side effects of plaquenil Common and Rare Side Effects for Plaquenil Oral, Plaquenil Indications, Side Effects, Warnings - Plaquenil and lasikHydroxychloroquine hair lighteningChloroquine function in lysosome Bad Side Effects of Plaquenil. I have been recently diagnosed with Lupus about 4 months ago and have started plaquenil with the hope it would relieve my symptoms no energy, achy body and severe hair loss. It seems as though it has helped the first two symptoms, but I have horrible constipation. Bad Side Effects of Plaquenil -. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil Side Effects Common, Severe, Long Term -. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Side effects are uncommon; however, a few people may develop a rash, indigestion, diarrhoea, headache, blurred vision, darkening of the skin, or bleaching of the hair. Hydroxychloroquine can aggravate pre-existing psoriasis.