So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Why take plaquenil with food Treatment of uncomplicated malaria chloroquine Cuando parar la hydroxychloroquine I had to stop Plaquenil after a few days. I couldn't walk, was dizzy, my speech was slurred, blurry vision, etc. but, I'm the one who usually gets side effects. I know people who Plaquenil has worked wonders. The side effects cleared up within a week. I also have Sjorgens, and my eyes were dryer on Plaquenil, but the blurry vision was the worst. Sep 15, 2014 Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Jan 11, 2012 Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Plaquenil toxicity after stopping Hydroxychloroquine MedlinePlus Drug Information, Retinal toxicity associated with chronic exposure to. How long to take plaquenil Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Rx Side Effects New Plaquenil Guidelines and More.. Let me tell you what weaning down from Plaquenil is like.. The Risk of Retinal Toxicity with Plaquenil. Patients in earlier stages of hydroxychloroquine retinal toxicity usually do not experience symptoms, though the rare patient may note a paracentral scotoma that causes trouble with reading as well as diminished color vision. However, most patients usually notice symptoms only after scotomas have become severe. Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. May 07, 2012 The only thing that helped was stopping the plaquenil after feeling better and some time I thought I’d try it again after a flare. About a month in body feels itchy can’t get comfortable after stopping the 200mg a day my anxiety is scary never felt this bad the only thing I’ve found to help is benadryl it relaxes my body.