PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Hydroxychloroquine what is it used for Is p falciparum chloroquine resistant Chloroquine prostate cancer Multifocal erg plaquenil toxicity Plaquenil Hydroxychloroquine Plaquenil is a prescription medication approved by the Food and Drug Administration FDA to treat inflammation associated with lupus in people whose symptoms have not responded to drugs with lower risk for side effects. Plaquenil is also known by its drug name, Hydroxychloroquine. The recommended Plaquenil dosage for malaria prevention is 400 mg once weekly, starting two weeks before the anticipated exposure. The usual starting dosage for treating lupus is 400 mg once or twice a day, and the recommended starting dose for the treatment of rheumatoid arthritis is 400 to 600 mg daily. Typical starting dose is 800 mg. This is followed by 400 mg three times 6 hours after the first dose, 24 hours after the first dose, and 48 hours after the first dose. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Plaquenil dosage for lupus Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Plaquenil Dosage - Antibiotics Home Page Plaquenil 200 mg film-coated tabletsDifference between chloroquine and quininePlaquenil side effects antimalarial Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. The recommended adult dose for rheumatoid arthritis is 400-600 mg daily for 4-12 weeks followed by 200-400 mg daily. Systemic lupus erythematosus is treated with 400 mg once or twice daily for several weeks then 200-400 mg daily. Hydroxychloroquine should be taken with food or milk in order to reduce stomach upset. Hydroxychloroquine may inhibit P-glycoprotein P-gp. Digoxin is a substrate for P-gp transport. For patients on a stable digoxin regimen and initiating hydroxychloroquine, no initial dose adjustment of either drug has been advised; however, serum digoxin concentrations should be monitored and used for digoxin dose titration as clinically.