She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Chloroquine nursing responsibilities Difference between hydroxychloroquine Macular Society is the trading name of the Macular Disease Society. A charity registered in England and Wales 1001198, Scotland SC042015. 1123 Isle of Man. A company limited by guarantee, registered in England No. 2177039. For individuals with significant risk factors daily dose of hydroxychloroquine sulfate greater than 5.0 mg/kg base of actual body weight, subnormal glomerular filtration, use of tamoxifen citrate or concurrent macular disease monitoring should include annual examinations which include BCVA, VF and SD-OCT. Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Plaquenill oct macula How to Succeed in Plaquenil Screenings, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Hydroxychloroquine bluelight OCT Interpretation in Retinal Disease Executive Clinical Director –Retina and Macula Specialists Jay M. Haynie, OD, FAAO Financial Disclosure I have received honoraria or am on the advisory board for the following companies Carl Zeiss Meditec Advanced Ocular Care Arctic DX –Macula Risk Genentech Lampa Advisory OCT Cross section of retinal. OCT Interpretation in Retinal Disease. The Risk of Retinal Toxicity with Plaquenil. Hydroxychloroquine Plaquenil Toxicity and.. Recent advances in spectral-domain optical coherence tomography SD-OCT allow for cross-sectional imaging of the retina in vivo to resolutions of 5 to 10 μm. 11 – 16 Adaptive optics AO imaging corrects for ocular aberrations and allows for direct visualization of the photoreceptor mosaic in vivo to resolutions of ≤2 μm. 17 – 20 This report presents the results of SD-OCT and AO imaging on two patients with known hydroxychloroquine retinopathy. Nov 01, 2015 H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. Ocular signs – Anterior segment - vortex keratopathy Fundus – bilateral multiple, yellow, crystalline, ring like deposits in the maculae. These persists even on cessation of treatment, macular edema, punctate retinal pigmentary changes Work up FFA – late focal staining in the macula consistent with CME.