How to make chloroquine poison

Discussion in 'Health Canada Drug Database' started by SANTIAGO, 15-Mar-2020.

  1. Lelik Guest

    How to make chloroquine poison


    A study in Uganda suggested around 3% of all cases of poisoning admitted to hospital had taken chloroquine: no other anti-malarial drugs were involved [1]. The commonly used drugs used to treat malaria in South Sudan are artemether with lumefantrine (as “Co-artem” or “Riamet”), artesunate and amodiaquine, quinine and occasionally doxycycline.

    Side effects of plaquenil mayo clinic Treatment of uncomplicated malaria chloroquine Plaquenil and folic acid

    For chloroquine, quinidine and quinine give repeated doses of charcoal for 24 hours adults, 50 g every 2-4 hours; children, 10-30 g every 2-4 hours. With each dose of charcoal give sodium sulfate or magnesium sulfate, 30 g to adults, 250 mg/kg of body weight to children, until the stools look black. Make sure there's a carbon monoxide alarm in every sleeping area of your home. Button batteries Be especially mindful of the 20 mm lithium coin cell. When swallowed by children, especially those younger than 4 years, it often lodges in the esophagus causing burns within just 2 hours. The cardiovascular effects of acute chloroquine intoxication have been described in three patients and in five animal experiments. The drug appears to act as a potent myocardial poison, reducing the output of the heart and causing disturbances of conduction bradycardia, and arrhythmias.

    Chloroquine[a] and quinine will be considered together as there are similarities in their toxic effects. Chloroquine is infrequently used because of parasite resistance but nevertheless will be included in this review.

    How to make chloroquine poison

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  7. Make a mixture by melting three ounces of unsalted butter and two tablespoons of beeswax in separate pans. When the beeswax has melted, mix in with the butter. Add five tablespoons ground juniper berries and three teaspoons ground cloves to the mixture and stir. Allow to cool and apply to the affected area before bedtime.

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    Both adults and children should take one dose of chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. Hemozoin collects in the digestive vacuole as insoluble crystals. Chloroquine enters the red blood cell, inhabiting parasite cell, and digestive vacuole by simple diffusion. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4. 7; chloroquine then cannot leave by diffusion. An overdose of chloroquine can be fatal, especially in children. Chloroquine overdose must be treated quickly. You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose.

     
  8. firmpepper User

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