Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. How quick will symptoms return after you stop plaquenil Hydroxychloroquine ncbi Apr 28, 2009 And, as far as Plaquenil and eye problems, the Ophthamologists I've talked to including a Neuro Ophthalmologist say that while Plaquenil can cause serious damage to the optic nerve, it's very rare. Annual appointments with an ophthalmologist are important in order to catch any problems early. Chronic fatigue is a common RA symptom. Discover six ways you can better manage fatigue and find more energy to deal with rheumatoid arthritis. Talk to your doctor about this, but my guess is that the Plaquenil is not doing anything to cause the pain, but rather that it is not doing enough to prevent it. It sounds like your RA has probably gotten a bit out of control, relative, to your current treatment, and Plaquenil is not a particularly potent drug when it comes to managing joint pain. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause extreme fatigue The Risk of Retinal Toxicity with Plaquenil, Chronic Fatigue From RA 6 Ways to Fight Back Everyday Health Plaquenil generico en mexicoBuy aralen 250Patient teaching when taking hydroxychloroquineHemozoin chloroquine I also have fatigue and mostly give up social activities in the evening so that I can work most of the day not a quality-of-life choice I like. So I think I will look more closely at these tips from Sarah Sjögrens fatigue – and all autoimmune fatigue – is a clinical conundrum. Sjögrens Fatigue – an Autoimmune Conundrum! SjögrensLife. Plaquenil and pain" Rheumatoid Arthritis Community.. Ask the Expert Plaquenil and Sjögren’s. Hi! I think Plaquenil is the cause of my extreme fatigue too. I am not anemic at this time and I get exhausted just trying to get through the day. I have also been on Plaquenil about three months. All of my arthritis swelling and pain are gone, but the fatigue will not let up! Hope things change for you. Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is. Chronic fatigue is a serious and debilitating condition, and it's often found among those with rheumatoid arthritis. Experts don't entirely understand the relationship between the two, but they have some ideas how they're connected.