PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Vitamin k and plaquenil Plaquenil newborn Chloroquine interactions with birth control The recommended adult dosage for a person with lupus is 200 to 400 mg daily. It can be taken in two doses or at one time. Doses above 400 mg/day are not recommended. It is possible to overdose on Plaquenil as it is rapidly and completely ignored upon ingestion. CHICAGO — Hydroxychloroquine has many indications, including systemic lupus erythematosus. In this setting, it has been shown to reduce flares, prevent organ damage, reduce cardiovascular risks. For individuals with significant risk factors daily dose of hydroxychloroquine sulfate 5.0 mg/kg base of actual body weight, subnormal glomerular filtration, use of tamoxifen citrate or concurrent macular disease monitoring should include annual examinations which include BCVA, VF and SD-OCT; for individuals without significant risk. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine lupus dosage Hydroxychloroquine User Reviews for Systemic Lupus., Experts debate hydroxychloroquine dosing guidelines in lupus Symptoms of plaquenil allergyPlaquenil nail discoloration SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. ACR Actual-weight hydroxychloroquine dosing works in SLE.. Plaquenil hydroxychloroquine sulfate dosing, indications.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. Discoid lupus erythematosus and subacute cutaneous lupus erythematosus For use if response to local therapy is inadequate or impractical due to widespread skin lesions Clarke 2019; Kuhn 2017 Oral 200 to 400 mg daily as a single daily dose or in 2 divided doses. Note Due to the risk of retinal toxicity. Hydroxychloroquine dosage recommendations often ignored. Publish date March 8, 2017. By. primarily for rheumatoid arthritis or systemic lupus erythematosus. Nearly two-thirds had a high risk for retinal toxicity. Based on the 2011 recommendations from the AAO and ACR, 17% of the patients were receiving an HCQ overdose that was more than 10%.