During sleep, when patients appear most still, their inflammatory systems are most active. Physicians who treat rheumatoid arthritis have long noted the morning stiffness that results. D., a professor of rheumatology at the University of Genoa, Italy, many physicians don’t take the next logical step: treating the inflammation with low-dose glucocorticoids administered at the night. Cutolo reviewed the literature on this approach in a recent article for the journal RMD Open. Plaquenil makes my body ache How long for plaquenil drug eruption to go away How does azithoprine work with plaquenil fir lupus But too often patients take prednisone between 6 a.m. and 8 a.m. says Dr. Cutolo, when it may come too late to curb the inflammation. “The best time, the optimal time, in chronic long-term treatment with low-dose glucocorticoids is availability at the time of maximum need Prednisone is also notorious for inducing fluid retention and high blood pressure by causing the body to retain sodium. Therefore, it is important to be cautious about your salt intake while taking prednisone. The 2010 Dietary Guidelines for Americans recommend consuming less than 1,500 milligrams of sodium per day if you have high blood pressure. Plaquenil and Prednisone is not even in the same class of drugs. The prednisone is a steriod and the plaquenil is a anti malaria drug. The thing with plaquenil for me is that I don't notice much of anything taking it but when I go off then I flare up and then really notice it. Studies as far back as 1964 have documented the advantages of treating inflammation at night. Not only does taking prednisone at bedtime work better, the newly available delayed-release formula (Rayos, Horizon Pharma) takes effect at 3 a.m., when it is needed the most, he says. Doi need to take prednisone with plaquenil Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Foods to Avoid When Taking Prednisone Chloroquine to buyDosage for chloroquine syrupChloroquine tablet price in indiaChloroquine dose in child Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Prednisone and Plaquenil DailyStrength. Prednisone and Plaquenil drug interactions - eHealthMe. Dec 19, 2011 Plaquenil - Will Plaquinil work without prednisone? I do not want to take the prednisone because of? Asked by lyn579 Updated 29 January 2012 Topics plaquenil, breast cancer, obesity, cancer, fibromyalgia, prednisone, side effect, weight, systemic lupus erythematosus, medical Plaquenil - Will Plaquinil work without prednisone? I do not want to take the prednisone because of? Asked by lyn579 Updated 29 January 2012 Topics plaquenil, breast cancer, obesity, cancer, fibromyalgia, prednisone, side effect, weight, systemic lupus erythematosus, medical May 12, 2008 Plaquenil can cause problems with eyesight, blood issues, liver and kidney damage. Unfortunately, if you do have Lupus, prednisone is your best choice to knock out the symptoms quickly. It should.